MT-ATP6 antibody (C-Term)
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- Target See all MT-ATP6 Antibodies
- MT-ATP6 (Mitochondrially Encoded ATP Synthase 6 (MT-ATP6))
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Binding Specificity
- C-Term
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MT-ATP6 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequence
- MNLSMAIPLW AGAVITGFRH KLKSSLAHFL PQGTPISLIP MLIIIETISL FIQPMALAVR LTANITAGHL LMHLIGGATL VLMNISPPTA TITFIILLLL TILEFAVALI QAYVFTLLVS LYLHDNT
- Cross-Reactivity
- Human, Mouse
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of mouse ATP6 (NP_904333.1).
- Isotype
- IgG
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- Application Notes
- WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200
- Comment
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HIGH QUALITY
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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WITHDRAWN:Mitochondrial targeting of HIF-1α inhibits hypoxia-induced apoptosis independently of its transcriptional activity." in: Free radical biology & medicine, (2018) (PubMed).
: "Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells." in: The international journal of biochemistry & cell biology, Vol. 89, pp. 42-56, (2017) (PubMed).
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WITHDRAWN:Mitochondrial targeting of HIF-1α inhibits hypoxia-induced apoptosis independently of its transcriptional activity." in: Free radical biology & medicine, (2018) (PubMed).
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- Target
- MT-ATP6 (Mitochondrially Encoded ATP Synthase 6 (MT-ATP6))
- Alternative Name
- MT-ATP6 (MT-ATP6 Products)
- Synonyms
- mtatp6 antibody, ATPase6 antibody, MTATP6 antibody, ATPase 6 antibody, ATP antibody, ATPIB antibody, CAMRQ4 antibody, IB antibody, ML-1 antibody, ATP synthase 6 antibody, ATP synthase F0 subunit 6 antibody, ATPase phospholipid transporting 8A2 antibody, ATPase subunit 6 antibody, H(+)-transporting ATPasesubunit 6 antibody, ATP6 antibody, ATP8A2 antibody, atp6 antibody
- Background
- Mitochondrial membrane ATP synthase (F(1F(0 ATP synthase or Complex V produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1 - containing the extramembraneous catalytic core and F(0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel, it may play a direct role in the translocation of protons across the membrane.,MT-ATP6,ATPase6,MTATP6,ATP6,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,Neurodegenerative Diseases,MT-ATP6
- Molecular Weight
- 25 kDa
- Gene ID
- 17705
- UniProt
- P00848
- Pathways
- Proton Transport, Ribonucleoside Biosynthetic Process
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