XRCC6BP1 antibody (AA 1-246)

Catalog No. ABIN6137312

Product Details anti-XRCC6BP1 Antibody

Target: XRCC6BP1 (XRCC6 Binding Protein 1 (XRCC6BP1))

Binding Specificity: AA 1-246

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XRCC6BP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MAGAPDERRR GPAAGEQLQQ QHVSCQVFPE RLAQGNPQQG FFSSFFTSNQ KCQLRLLKTL ETNPYVKLLL DAMKHSGCAV NKDRHFSCED CNGNVSGGFD ASTSQIVLCQ NNIHNQAHMN RVVTHELIHA FDHCRAHVDW FTNIRHLACS EVRAANLSGD CSLVNEIFRL HFGLKQHHQT CVRDRATLSI LAVRNISKEV AKKAVDEVFE SCFNDHEPFG RIPHNKTYAR YAHRDFENRD RYYSNI

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human ATP23 (NP_150592.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:3000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for XRCC6BP1

Target: XRCC6BP1 (XRCC6 Binding Protein 1 (XRCC6BP1))

Alternative Name: ATP23 (XRCC6BP1 Products)

Background: The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.,ATP23,KUB3,XRCC6BP1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,ATP23

Molecular Weight: 28 kDa

Gene ID: 91419

UniProt: Q9Y6H3