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ATIC antibody (AA 1-300)

ATIC Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6137273
  • Target See all ATIC Antibodies
    ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))
    Binding Specificity
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-300
    Reactivity
    • 51
    • 26
    • 21
    • 10
    • 9
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 40
    • 11
    Rabbit
    Clonality
    • 41
    • 10
    Polyclonal
    Conjugate
    • 34
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This ATIC antibody is un-conjugated
    Application
    • 33
    • 12
    • 11
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MAPGQLALFS VSDKTGLVEF ARNLTALGLN LVASGGTAKA LRDAGLAVRD VSELTGFPEM LGGRVKTLHP AVHAGILARN IPEDNADMAR LDFNLIRVVA CNLYPFVKTV ASPGVTVEEA VEQIDIGGVT LLRAAAKNHA RVTVVCEPED YVVVSTEMQS SESKDTSLET RRQLALKAFT HTAQYDEAIS DYFRKQYSKG VSQMPLRYGM NPHQTPAQLY TLQPKLPITV LNGAPGFINL CDALNAWQLV KELKEALGIP AAASFKHVSP AGAAVGIPLS EDEAKVCMVY DLYKTLTPIS
    Cross-Reactivity
    Human
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ATIC (NP_004035.2).
    Isotype
    IgG
    Top Product
    Discover our top product ATIC Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Comment

    HIGH QUALITY

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))
    Alternative Name
    ATIC (ATIC Products)
    Synonyms
    AICAR antibody, AICARFT antibody, IMPCHASE antibody, PURH antibody, purH antibody, 2610509C24Rik antibody, AA536954 antibody, AW212393 antibody, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase L homeolog antibody, bifunctional purine biosynthesis protein PurH antibody, bifunctional purine biosynthesis protein purH antibody, Bifunctional purine biosynthesis protein purH antibody, Bifunctional purine biosynthesis protein PurH antibody, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase antibody, atic.L antibody, purH antibody, ATIC antibody, Atic antibody
    Background
    This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.,ATIC,AICAR,AICARFT,HEL-S-70p,IMPCHASE,PURH,Epigenetics & Nuclear Signaling,Signal Transduction,Endocrine & Metabolism,Nucleotide metabolism,ATIC
    Molecular Weight
    64 kDa
    Gene ID
    471
    UniProt
    P31939
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