ATG9A antibody (AA 180-290)

Catalog No. ABIN6137269

Product Details anti-ATG9A Antibody

Target: ATG9A (ATG9 Autophagy Related 9 Homolog A (S. Cerevisiae) (ATG9A))

Binding Specificity: AA 180-290

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG9A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: WQEVQARIVQ TQKEHQICIH KRELTELDIY HRILRFQNYM VALVNKSLLP LRFRLPGLGE AVFFTRGLKY NFELILFWGP GSLFLNEWSL KAEYKRGGQR LELAQRLSNR I

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-290 of human ATG9A (NP_076990.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATG9A

Target: ATG9A (ATG9 Autophagy Related 9 Homolog A (S. Cerevisiae) (ATG9A))

Alternative Name: ATG9A (ATG9A Products)

Synonyms: ATG9 antibody, ATG9A antibody, zgc:158700 antibody, APG9L1 antibody, DKFZp459N117 antibody, MGD3208 antibody, mATG9 antibody, AU019532 antibody, Apg9l1 antibody, Atg9 antibody, Atg9l1 antibody, RGD1310450 antibody, autophagy related 9A antibody, ATG9 autophagy related 9 homolog A (S. cerevisiae) antibody, ATG9A antibody, atg9a antibody, Atg9a antibody

Background: Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion. Cycles between the preautophagosomal structure/phagophore assembly site (PAS and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 (ATG2A or ATG2B from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion. Also required to supply phosphatidylinositol 4-phosphate to the autophagosome initiation site by recruiting the phosphatidylinositol 4-kinase beta (PI4KB in a process dependent on ARFIP2, but not ARFIP1. In addition to autophagy, also plays a role in necrotic cell death (By similarity.,ATG9A,APG9L1,MGD3208,mATG9,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Ubiquitin,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Heart,ATGs,ATG9A

Molecular Weight: 60 kDa/87 kDa/94 kDa

Gene ID: 79065

UniProt: Q7Z3C6