Liver Arginase antibody (AA 1-322)

Catalog No. ABIN6137075

Product Details anti-Liver Arginase Antibody

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Binding Specificity: AA 1-322

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Liver Arginase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MSAKSRTIGI IGAPFSKGQP RGGVEEGPTV LRKAGLLEKL KEQECDVKDY GDLPFADIPN DSPFQIVKNP RSVGKASEQL AGKVAEVKKN GRISLVLGGD HSLAIGSISG HARVHPDLGV IWVDAHTDIN TPLTTTSGNL HGQPVSFLLK ELKGKIPDVP GFSWVTPCIS AKDIVYIGLR DVDPGEHYIL KTLGIKYFSM TEVDRLGIGK VMEETLSYLL GRKKRPIHLS FDVDGLDPSF TPATGTPVVG GLTYREGLYI TEEIYKTGLL SGLDIMEVNP SLGKTPEEVT RTVNTAVAIT LACFGLAREG NHKPIDYLNP PK

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-322 of human Arginase 1 (ARG1) (NP_000036.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-Liver Arginase antibody (ABIN6137075)

Yu, Ding, Liang, Luo: "Porphyromonas gingivalis inhibits M2 activation of macrophages by suppressing α-ketoglutarate production in mice." in: Molecular oral microbiology, Vol. 33, Issue 5, pp. 388-395, (2019) (PubMed).

Hou, Han, Fei, Gao, Qi, Cai, Qi: "Dietary Flavone Tectochrysin Exerts Anti-Inflammatory Action by Directly Inhibiting MEK1/2 in LPS-Primed Macrophages." in: Molecular nutrition & food research, Vol. 62, Issue 2, (2018) (PubMed).

Target Details for Liver Arginase

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Alternative Name: ARG1 (ARG1 Products)

Synonyms: SI:zC146F4.4 (novel protein with NUDIX domain) antibody, si:ch211-146f4.3 antibody, argi1 antibody, AI antibody, AI256583 antibody, Arg-1 antibody, PGIF antibody, arginase 1 antibody, arginase antibody, Arginase-1 antibody, arginase, liver antibody, L-arginase antibody, arg1 antibody, PGTG_16455 antibody, argi1 antibody, ARG1 antibody, Arg1 antibody

Background: Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.,ARG1,arginase-1,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,ARG1

Molecular Weight: 25 kDa/34 kDa/35 kDa

Gene ID: 383

UniProt: P05089

Pathways: Cellular Response to Molecule of Bacterial Origin