ANAPC5 antibody (AA 1-250)

Catalog No. ABIN6136867

Product Details anti-ANAPC5 Antibody

Target: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Binding Specificity: AA 1-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANAPC5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Sequence: MASVHESLYF NPMMTNGVVH ANVFGIKDWV TPYKIAVLVL LNEMSRTGEG AVSLMERRRL NQLLLPLLQG PDITLSKLYK LIEESCPQLA NSVQIRIKLM AEGELKDMEQ FFDDLSDSFS GTEPEVHKTS VVGLFLRHMI LAYSKLSFSQ VFKLYTALQQ YFQNGEKKTV EDADMELTSR DEGERKMEKE ELDVSVREEE VSCSGPLSQK QAEFFLSQQA SLLKNDETKA LTPASLQKEL NNLLKFNPDF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ANAPC5 (NP_057321.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ANAPC5

Target: ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))

Alternative Name: ANAPC5 (ANAPC5 Products)

Synonyms: APC5 antibody, DDBDRAFT_0206386 antibody, DDBDRAFT_0234269 antibody, DDB_0206386 antibody, DDB_0234269 antibody, zgc:55800 antibody, wu:fb75a09 antibody, ANAPC5 antibody, MGC89697 antibody, 2510006G12Rik antibody, AA408751 antibody, AA536819 antibody, AA986414 antibody, Anpc5 antibody, F12K11.7 antibody, F12K11_7 antibody, anaphase promoting complex subunit 5 antibody, anaphase-promoting complex subunit 5 antibody, anaphase promoting complex subunit 5 L homeolog antibody, anaphase-promoting complex subunit antibody, anaphase-promoting complex subunit Apc5 antibody, ANAPC5 antibody, anapc5 antibody, LOC100093215 antibody, anapc5.L antibody, Anapc5 antibody, AT1G06590 antibody, apc5 antibody

Background: This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.,ANAPC5,APC5,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,ANAPC5

Molecular Weight: 25 kDa/72 kDa/85 kDa

Gene ID: 51433

UniProt: Q9UJX4

Pathways: M Phase