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ALKBH5 antibody (AA 245-394)

ALKBH5 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6136806
  • Target See all ALKBH5 Antibodies
    ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
    Binding Specificity
    • 15
    • 7
    • 7
    • 6
    • 6
    • 2
    AA 245-394
    Reactivity
    • 25
    • 24
    • 17
    Human
    Host
    • 38
    • 2
    Rabbit
    Clonality
    • 40
    Polyclonal
    Conjugate
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ALKBH5 antibody is un-conjugated
    Application
    • 18
    • 18
    • 13
    • 13
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    SLPVRRGSVT VLSGYAADEI THCIRPQDIK ERRAVIILRK TRLDAPRLET KSLSSSVLPP SYASDRLSGN NRDPALKPKR SHRKADPDAA HRPRILEMDK EENRRSVLLP THRRRGSFSS ENYWRKSYES SEDCSEAAGS PARKVKMRRH
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 245-394 of human ALKBH5 (NP_060228.3).
    Isotype
    IgG
    Top Product
    Discover our top product ALKBH5 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
    Alternative Name
    ALKBH5 (ALKBH5 Products)
    Synonyms
    RGD1309496 antibody, ABH5 antibody, OFOXD antibody, OFOXD1 antibody, AW050020 antibody, AW215868 antibody, Abh5 antibody, E130207K11 antibody, Ofoxd antibody, alkB homolog 5, RNA demethylase antibody, alkB homolog 5, RNA demethylase L homeolog antibody, Alkbh5 antibody, alkbh5.L antibody, ALKBH5 antibody
    Background
    Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6-methyladenosine (m6A RNA, the most prevalent internal modification of messenger RNA (mRNA in higher eukaryotes. Can also demethylate N(6-methyladenosine in single-stranded DNA (in vitro. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export. Required for the late meiotic and haploid phases of spermatogenesis by mediating m6A demethylation in spermatocytes and round spermatids: m6A demethylation of target transcripts is required for correct splicing and the production of longer 3'-UTR mRNAs in male germ cells (By similarity.,ALKBH5,ABH5,OFOXD,OFOXD1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,RNA Binding,ALKBH5
    Molecular Weight
    43 kDa/44 kDa/52 kDa
    Gene ID
    54890
    UniProt
    Q6P6C2
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