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P5CS antibody (AA 1-240)

ALDH18A1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6136762
  • Target See all P5CS (ALDH18A1) Antibodies
    P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))
    Binding Specificity
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-240
    Reactivity
    • 20
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 15
    • 4
    • 1
    Rabbit
    Clonality
    • 18
    • 2
    Polyclonal
    Conjugate
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    This P5CS antibody is un-conjugated
    Application
    • 20
    • 13
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MLSQVYRCGF QPFNQHLLPW VKCTTVFRSH CIQPSVIRHV RSWSNIPFIT VPLSRTHGKS FAHRSELKHA KRIVVKLGSA VVTRGDECGL ALGRLASIVE QVSVLQNQGR EMMLVTSGAV AFGKQRLRHE ILLSQSVRQA LHSGQNQLKE MAIPVLEARA CAAAGQSGLM ALYEAMFTQY SICAAQILVT NLDFHDEQKR RNLNGTLHEL LRMNIVPIVN TNDAVVPPAE PNSDLQGVNV
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ALDH18A1 (NP_002851.2).
    Isotype
    IgG
    Top Product
    Discover our top product ALDH18A1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))
    Alternative Name
    ALDH18A1 (ALDH18A1 Products)
    Synonyms
    ALDH18A1 antibody, ARCL3A antibody, GSAS antibody, P5CS antibody, PYCS antibody, 2810433K04Rik antibody, AI429789 antibody, Pycs antibody, cb842 antibody, cb899 antibody, pycs antibody, sb:cb881 antibody, wu:fa91f10 antibody, wu:fi05f11 antibody, wu:fi17d12 antibody, aldehyde dehydrogenase 18 family member A1 antibody, aldehyde dehydrogenase 18 family, member A1 antibody, aldehyde dehydrogenase 18 family member A1 L homeolog antibody, ALDH18A1 antibody, aldh18a1 antibody, Aldh18a1 antibody, aldh18a1.L antibody
    Background
    This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.,ALDH18A1,ADCL3,ARCL3A,GSAS,P5CS,PYCS,SPG9,SPG9A,SPG9B,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,ALDH18A1
    Molecular Weight
    87 kDa
    Gene ID
    5832
    UniProt
    P54886
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