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ALAS1 antibody (AA 1-250)
ALAS1
Reactivity: Human
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ALAS1 Antibody
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Target
See all ALAS1 Antibodies
ALAS1
(Aminolevulinate, delta-, Synthase 1 (ALAS1))
Binding Specificity
All epitopes for ALAS1 antibodies
AA 1-250
Reactivity
All reactivities for ALAS1 antibodies
Human
Host
All hosts for ALAS1 antibodies
Rabbit
Clonality
All clonalities for ALAS1 antibodies
Polyclonal
Conjugate
All conjugates for ALAS1 antibodies
This ALAS1 antibody is un-conjugated
Application
All applications for ALAS1 antibodies
Western Blotting (WB), Immunofluorescence (IF)
Sequence
MESVVRRCPF LSRVPQAFLQ KAGKSLLFYA QNCPKMMEVG AKPAPRALST AAVHYQQIKE TPPASEKDKT AKAKVQQTPD GSQQSPDGTQ LPSGHPLPAT SQGTASKCPF LAAQMNQRGS SVFCKASLEL QEDVQEMNAV RKEVAETSAG PSVVSVKTDG GDPSGLLKNF QDIMQKQRPE RVSHLLQDNL PKSVSTFQYD RFFEKKIDEK KNDHTYRVFK TVNRRAHIFP MADDYSDSLI TKKQVSVWCS
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ALAS1 (NP_954635.1).
Isotype
IgG
Top Product
Discover our top product ALAS1 Primary Antibody
Alternatives
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anti-Aminolevulinate, delta-, Synthase 1 (ALAS1) (AA 146-195) antibody
ALAS1
Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Monkey
WB, IHC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB,1:500 - 1:2000,IF,1:50 - 1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for ALAS1
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Target
ALAS1
(Aminolevulinate, delta-, Synthase 1 (ALAS1))
Alternative Name
ALAS1 (ALAS1 Products )
Synonyms
ALAS antibody, ALAS3 antibody, ALASH antibody, MIG4 antibody, ALAS-N antibody, Alas-1 antibody, Alas-h antibody, ALAS-H antibody, ALASN antibody, ALAS1 antibody, wu:fb58d01 antibody, wu:fi12g09 antibody, 5'-aminolevulinate synthase 1 antibody, aminolevulinic acid synthase 1 antibody, alanyl-tRNA synthetase protein antibody, aminolevulinate, delta-, synthase 1 antibody, ALAS1 antibody, Alas1 antibody, alas1 antibody, alas1.S antibody, alaS1 antibody
Background
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.,ALAS1,ALAS,ALAS-H,ALAS3,ALASH,MIG4,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Cardiovascular,Blood,ALAS1
Molecular Weight
12 kDa/70 kDa
Gene ID
211
UniProt
P13196
Pathways
Regulation of Lipid Metabolism by PPARalpha
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