ADAM8 antibody (AA 17-300)

Catalog No. ABIN6136536

Product Details anti-ADAM8 Antibody

Target: ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))

Binding Specificity: AA 17-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IAPSRPWALM EQYEVVLPWR LPGPRVRRAL PSHLGLHPER VSYVLGATGH NFTLHLRKNR DLLGSGYTET YTAANGSEVT EQPRGQDHCF YQGHVEGYPD SAASLSTCAG LRGFFQVGSD LHLIEPLDEG GEGGRHAVYQ AEHLLQTAGT CGVSDDSLGS LLGPRTAAVF RPRPGDSLPS RETRYVELYV VVDNAEFQML GSEAAVRHRV LEVVNHVDKL YQKLNFRVVL VGLEIWNSQD RFHVSPDPSV TLENLLTWQA RQRTRRHLHD NVQLITGVDF TGTT

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 17-300 of human ADAM8 (NP_001100.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ADAM8

Target: ADAM8 (ADAM Metallopeptidase Domain 8 (ADAM8))

Alternative Name: ADAM8 (ADAM8 Products)

Background: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.,ADAM8,CD156,CD156a,MS2,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Extracellular Matrix,ADAM Protein Family,Ubiquitin,Immunology & Inflammation,CD markers,ADAM8

Molecular Weight: 78 kDa/80 kDa/88 kDa

Gene ID: 101

UniProt: P78325

Pathways: Activation of Innate immune Response, M Phase