ADAM12 antibody (AA 589-738)

Catalog No. ABIN6136521

Product Details anti-ADAM12 Antibody

Target: ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))

Binding Specificity: AA 589-738

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM12 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: ASRPVIGTNA VSIETNIPLQ QGGRILCRGT HVYLGDDMPD PGLVLAGTKC ADGKICLNRQ CQNISVFGVH ECAMQCHGRG VCNNRKNCHC EAHWAPPFCD KFGFGGSTDS GPIRQAEARQ EAAESNRERG QGQEPVGSQE HASTASLTLI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 589-738 of human ADAM12 (NP_067673.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ADAM12

Target: ADAM12 (ADAM Metallopeptidase Domain 12 (ADAM12))

Alternative Name: ADAM12 (ADAM12 Products)

Background: This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form.,ADAM12,ADAM12-OT1,CAR10,MCMP,MCMPMltna,MLTN,MLTNA,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Extracellular Matrix,ADAM Protein Family,Ubiquitin,ADAM12

Molecular Weight: 80 kDa/99 kDa

Gene ID: 8038

UniProt: O43184

Pathways: EGFR Signaling Pathway