ACSL3 antibody, acsl3 antibody, fa07a08 antibody, im:7155129 antibody, si:dkey-20f20.5 antibody, wu:fa07a08 antibody, wu:fb34c03 antibody, si:dkeyp-109h9.2 antibody, ACS3 antibody, FACL3 antibody, PRO2194 antibody, 2610510B12Rik antibody, Acs3 antibody, C85929 antibody, Facl3 antibody, Pro2194 antibody, F15H21.7 antibody, F15H21_7 antibody, long-chain acyl-CoA synthetase 3 antibody, acyl-CoA synthetase long-chain family member 3 antibody, acyl-CoA synthetase long chain family member 3 antibody, acyl-CoA synthetase long chain family member 3b antibody, acyl-CoA synthetase long chain family member 3a antibody, AcsL3 antibody, AMP-dependent synthetase and ligase family protein antibody, ACSL3 antibody, acsl3b antibody, acsl3a antibody, acsL3 antibody, acsl3 antibody, Acsl3 antibody, LACS3 antibody
Background
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92 % identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene.,ACSL3,ACS3,FACL3,PRO2194,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Lipids,Fatty Acids,ACSL3