ACLY antibody (pSer455)
-
- Target See all ACLY Antibodies
- ACLY (ATP Citrate Lyase (ACLY))
-
Binding Specificity
- pSer455
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This ACLY antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Sequence
- TASFS
- Cross-Reactivity
- Mouse, Rat
- Characteristics
- Phosphorylated Antibodies
- Purification
- Affinity purification
- Immunogen
- A synthetic phosphorylated peptide around S455 of human ACLY (NP_001087.2).
- Isotype
- IgG
- Top Product
- Discover our top product ACLY Primary Antibody
-
-
- Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IP,1:50 - 1:100
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- ACLY (ATP Citrate Lyase (ACLY))
- Alternative Name
- ACLY (ACLY Products)
- Background
- ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.,ACLY,ACL,ATPCL,CLATP,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Insulin Receptor Signaling Pathway,Warburg Effect,Protein phosphorylation,ACLY
- Molecular Weight
- 91 kDa/119 kDa/120 kDa
- Gene ID
- 47
- UniProt
- P53396
- Pathways
- Warburg Effect
-