NOP56 antibody

Catalog No. ABIN5961760

Product Details anti-NOP56 Antibody

Target: NOP56 (NOP56 Ribonucleoprotein Homolog (NOP56))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOP56 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: NOL5A,NOP56,NOP56 ribonucleoprotein,NOP56 ribonucleoprotein homolog (yeast),NOP56 ribonucleoprotein homolog,Nucleolar protein 56,Nucleolar protein 5A (56kD with KKE/D repeat),Nucleolar protein 5A,Nucleolar protein Nop56,RP4-686C3.1,SCA36

Purification: Affinity purification

Immunogen: Synthesized peptide derived from NOP56

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol  pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NOP56

Target: NOP56 (NOP56 Ribonucleoprotein Homolog (NOP56))

Alternative Name: NOP56 (NOP56 Products)

Background: NOP56 (NOP56 Ribonucleoprotein) is a Protein Coding gene. Diseases associated with NOP56 include Spinocerebellar Ataxia 36 and Spinocerebellar Ataxia Type36. Among its related pathways are Chaperonin-mediated protein folding and rRNA processing in the nucleus and cytosol. GO annotations related to this gene include poly(A) RNA binding and snoRNA binding.Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined.

Molecular Weight: 66kDa

Gene ID: 10528

UniProt: O00567