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CaMKIIbeta/gamma/delta antibody (pThr287)

Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5960666
  • Target See all CaMKIIbeta/gamma/delta products
    CaMKIIbeta/gamma/delta
    Binding Specificity
    • 3
    • 1
    • 1
    • 1
    pThr287
    Reactivity
    Human, Mouse, Rat
    Host
    • 4
    • 1
    Rabbit
    Clonality
    • 4
    • 1
    Polyclonal
    Conjugate
    • 5
    This CaMKIIbeta/gamma/delta antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Specificity
    CAMK2B,CAM2,CAMK2,CAMKB,Calcium/calmodulin-dependent protein kinase type II subunit beta,CaM kinase II subunit beta,CaMK-II subunit beta,CAMK2G,CAMK,CAMK-II,CAMKG,Calcium/calmodulin-dependent protein kinase type II subunit gamma,
    Purification
    Affinity purification
    Immunogen
    Synthesized peptide derived from human CaMKIIbeta/gamma/delta around the phosphorylation site of Thr287
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:5000
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CaMKIIbeta/gamma/delta
    Abstract
    CaMKIIbeta/gamma/delta Products
    Background
    The product of CAMK2B belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. CAMK2B (Calcium/Calmodulin Dependent Protein Kinase II Beta) is a Protein Coding gene. Diseases associated with CAMK2B include Phencyclidine Abuse. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and Development Endothelin-1/EDNRA signaling. GO annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is CAMK2G. The product of CAMK2G is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined. CAMK2G (Calcium/Calmodulin Dependent Protein Kinase II Gamma) is a Protein Coding gene. Diseases associated with CAMK2G include Timothy Syndrome and Exudative Vitreoretinopathy. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and Development Endothelin-1/EDNRA signaling. GO annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is CAMK2B. The product of CAMK2D belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.CAMK2D (Calcium/Calmodulin Dependent Protein Kinase II Delta) is a Protein Coding gene. Diseases associated with CAMK2D include Dilated Cardiomyopathy and Cardiomyopathy. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and Development Endothelin-1/EDNRA signaling. GO annotations related to this gene include protein homodimerization activity and protein kinase activity. An important paralog of this gene is CAMK2B.
    Molecular Weight
    56-72kDa
    Gene ID
    816, 818, 817
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