CMKLR1 antibody
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- Target See all CMKLR1 Antibodies
- CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CMKLR1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- CHEMERINR,Chemokine like receptor 1,Chemokine-like receptor 1,CHEMR23,CMKLR1,CML1,DEZ,G protein coupled receptor ChemR23,G protein coupled receptor DEZ,G-protein coupled receptor ChemR23,G-protein coupled receptor DEZ,Orphan G protein coupled receptor,Orphan G protein coupled receptor Dez,Resolvin E1 receptor,RVER1
- Purification
- Affinity purification
- Immunogen
- Synthesized peptide derived from the Internal region of human ChemR23
- Isotype
- IgG
- Top Product
- Discover our top product CMKLR1 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
- Alternative Name
- ChemR23 (CMKLR1 Products)
- Synonyms
- CHEMERINR antibody, ChemR23 antibody, DEZ antibody, RVER1 antibody, Gpcr27 antibody, mcmklr1 antibody, si:ch211-240b21.3 antibody, CMLKR1 antibody, Cmklr-1 antibody, GPCR antibody, chemerin chemokine-like receptor 1 antibody, chemokine-like receptor 1 antibody, CMKLR1 antibody, Cmklr1 antibody, cmklr1 antibody
- Background
- Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
- Molecular Weight
- 42kDa
- Gene ID
- 1240
- UniProt
- Q99788
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