Neisseria Meningitidis antibody (N-Term)

Catalog No. ABIN576732

Product Details anti-Neisseria Meningitidis Antibody

Target: Neisseria Meningitidis

Binding Specificity: N-Term

Reactivity: Neisseria meningitidis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neisseria Meningitidis antibody is un-conjugated

Application: Immunofluorescence (IF), ELISA

Specificity: Reacts with Neisseria meningitidis serogroups A, B and C and is thought to recognize all antigens. Other serogroups have not been tested. N. meningitidis is a gram-negative bacteria that is the causative agent of meningitis. There are 13 known significant serogroups that are classified according to the structure of their polysaccharide capsule. Serogroups, A, B, C, D, X, Y, Z, 29E and W135 are responsible for virtually all cases of the human disease. The carbohydrate component of the capsular membrane induces a T cell independent immune response, so neither long term immunity by memory cell formation nor antibody affinity maturation is observed. Rather than being engulfed and processed by an antigen presenting cell, the carbohydrate capsule interacts directly with B cells. This interaction causes production of serogroup specific antibodies, primarily IgM. IgG is also produced with an IgG1 response predominating in children and an IgG2 response predominating in adults.

Purification: Purified

Immunogen: Whole cell preparation of N. meningitidis types A, B and C.

Type of Immunogen: Cells

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Neisseria meningitidis

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Short term: -20°C
Long term: -20°C.

Target Details for Neisseria Meningitidis

Target: Neisseria Meningitidis

Abstract: Neisseria Meningitidis Products

Target Type: Bacteria