SLAMF1 antibody (APC)
-
- Target See all SLAMF1 Antibodies
- SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This SLAMF1 antibody is conjugated to APC
-
Application
- Flow Cytometry (FACS)
- Specificity
- The mouse monoclonal antibody SLAM.4 recognizes an extracellular epitope of CD150, a cell surface molecule expressed on lymphocytes and involved in their activation.
- Cross-Reactivity (Details)
- Human
- Purification
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogen
- Human CD150-transfected 300.19 cells
- Clone
- SLAM-4
- Isotype
- IgG1
- Top Product
- Discover our top product SLAMF1 Primary Antibody
-
-
- Application Notes
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- Comment
-
The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- Restrictions
- For Research Use only
-
- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
-
- Target
- SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
- Alternative Name
- CD150 (SLAMF1 Products)
- Synonyms
- CD150 antibody, SLAM antibody, SLAMF1 antibody, 4933415F16 antibody, AA177906 antibody, CDw150 antibody, ESTM51 antibody, IPO-3 antibody, Slam antibody, RGD1560634 antibody, signaling lymphocytic activation molecule family member 1 antibody, SLAMF1 antibody, Slamf1 antibody
- Background
- Signaling lymphocytic activation molecule family m,CD150, also known as SLAM (signaling lymphocyte activation molecule) is a 70-95 kDa single chain transmembrane phosphoglycoprotein of the CD2 family. Its extracellular part contains eight potential N-glycosylation sites, and the intracellular tail contains three unique tyrosine-based motifs. These binding sites can be recognized by SH2-binding phosphatases and the adaptor proteins, such as SAP/SH2D1A or EAT-2. The SLAM family receptors are involved in leucocyte activation and contribute to the effective germinal center formation, generation of high-affinity antibody-secreting plasma cells, and memory T and B cells, thereby facilitating long-term immune response. CD150 expression is upregulated after cell activation.,SLAM, SLAMF1
- Gene ID
- 6504
- UniProt
- Q13291
-