GHITM antibody (Internal Region)

Catalog No. ABIN571105

Product Details anti-GHITM Antibody

Target: GHITM (Growth Hormone Inducible Transmembrane Protein (GHITM))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This GHITM antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purpose: MICS1 / GHITM

Sequence: PSREYATKTR IGIR

Cross-Reactivity: Cow, Dog, Human, Mouse, Pig, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Verified

Immunogen: Peptide with sequence C-PSREYATKTRIGIR, from the internal region of the protein sequence according to NP_055209.2.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 35 kDa band observed in lysates of cell line HeLa and of Human Brain (Cerebellum), Duodenum and Heart (calculated MW of 37.2 kDa according to Human NP_055209.2). Recommended concentration: 0.01-0.1 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:8000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

References for anti-GHITM antibody (ABIN571105)

Meng, Yamashita, Shiba-Fukushima, Inoshita, Funayama, Sato, Hatta, Natsume, Umitsu, Takagi, Imai, Hattori: "Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c." in: Nature communications, Vol. 8, pp. 15500, (2018) (PubMed).

Target Details for GHITM

Target: GHITM (Growth Hormone Inducible Transmembrane Protein (GHITM))

Alternative Name: GHITM (GHITM Products)

Background: GHITM, growth hormone inducible transmembrane protein, DERP2, DKFZp566C0746, FLJ26584, HSPC282, MICS1, My021, PTD010, TMBIM5, dermal papilla-derived protein 2, mitochondrial morphology and cristae structure 1, transmembrane BAX inhibitor motif containing

Gene ID: 27069, 66092, 290596

NCBI Accession: NP_055209

Pathways: SARS-CoV-2 Protein Interactome