PSD
Reactivity: Human
WB, IF
Host: Mouse
Polyclonal
unconjugated
Application Notes
Optimal dilution of the PSD antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (recombinant human protein) (BSA-free format available)
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
-20 °C
Storage Comment
After reconstitution, the PSD antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Target
PSD
(Pleckstrin and Sec7 Domain Protein (PSD))
Alternative Name
PSD / PH and SEC7 domain-containing protein 1 (PSD Products)
PSD, also called EFA6A, is 63 % identical to EFA6B (PSD4) and contains a Sec7 domain adjacent to a PH domain, followed by a C-terminal coiled-coil motif. This gene is mapped to chromosome 10q24. And it encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants.