PAX5 antibody

Catalog No. ABIN5708263

Product Details anti-PAX5 Antibody

Target: PAX5 (Paired Box 5 (PAX5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAX5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogen: A recombinant human partial protein corresponding to amino acids R217-A282 was used as the immunogen for the PAX5 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PAX5 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the PAX5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for PAX5

Target: PAX5 (Paired Box 5 (PAX5))

Alternative Name: PAX5 (PAX5 Products)

Synonyms: PAX5 antibody, BSAP antibody, Pax-5 antibody, pax5-a antibody, RGD1565236 antibody, EBB-1 antibody, KLP antibody, Pax[Zf-b] antibody, noi antibody, pax2.1 antibody, pax2a antibody, paxzf-b antibody, paired box 5 antibody, paired box 5 L homeolog antibody, PAX5 antibody, pax5.L antibody, Pax5 antibody, pax5 antibody

Background: Paired box protein Pax-5 is a protein that in humans is encoded by the PAX5 gene. The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.

UniProt: Q02548