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PDK1 antibody (AA 107-336)

PDK1 Reactivity: Human, Rat WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5708184
  • Target See all PDK1 Antibodies
    PDK1 (Pyruvate Dehydrogenase Kinase 1 (PDK1))
    Binding Specificity
    • 7
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    AA 107-336
    Reactivity
    • 25
    • 19
    • 10
    • 1
    • 1
    • 1
    • 1
    Human, Rat
    Host
    • 28
    • 1
    Rabbit
    Clonality
    • 28
    • 1
    Polyclonal
    Conjugate
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This PDK1 antibody is un-conjugated
    Application
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity purified
    Immunogen
    A recombinant human protein corresponding to amino acids V107-Y336 was used as the immunogen for the PDK1 antibody.
    Isotype
    IgG
    Top Product
    Discover our top product PDK1 Primary Antibody
  • Application Notes
    Optimal dilution of the PDK1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL, IHC (FFPE): 1-2 μg/mL, Direct ELISA: 0.1-0.5 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the PDK1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    PDK1 (Pyruvate Dehydrogenase Kinase 1 (PDK1))
    Alternative Name
    PDK1 / Pyruvate Dehydrogenase Kinase 1 (PDK1 Products)
    Synonyms
    ATP5A antibody, B830012B01 antibody, D530020C15Rik antibody, si:zfos-979f1.3 antibody, 3-phosphoinositide dependent protein kinase-1 antibody, pyruvate dehydrogenase kinase 1 antibody, ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9) antibody, pyruvate dehydrogenase kinase, isoenzyme 1 antibody, pyruvate dehydrogenase kinase, isozyme 1 antibody, pyruvate dehydrogenase kinase 1 L homeolog antibody, Pdpk1 antibody, PDK1 antibody, ATP5G2 antibody, Pdk1 antibody, pdk1 antibody, pdk1.L antibody
    Background
    PDK1 (Pyruvate Dehydrogenase Kinase Isoenzyme 1), is an enzyme that in humans is encoded by the PDK1 gene. To find human PDKs, Gudi et al. (1995) used oligonucleotide primers to screen a human liver cDNA library by PCR. They identified and reported the deduced amino acid sequences of PDK1, PDK2, and PDK3. The human PDK1 gene encodes a protein with a predicted molecular mass of 49,244 Da that shares 93 % identity with that of the rat PDK1 gene. Northern blot analysis showed that the PDK1 message was expressed predominantly in the heart.
    UniProt
    Q15118
    Pathways
    PI3K-Akt Signaling, RTK Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Warburg Effect
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