Verified
ABCC1
Reactivity: Human
WB, ELISA
Host: Goat
Polyclonal
unconjugated
Application Notes
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the MRP1 antibody to be titered up or down for optimal performance.\. Western blot: 0.5-1 μg/mL,FACS: 0.5-1 μg/10^6 cells,Immunofluorescence: 1-2 μg/mL
Restrictions
For Research Use only
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Preservative
Azide free
Storage
4 °C,-20 °C
Storage Comment
Store the MRP1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Target
ABCC1
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1))
ABC29 antibody, ABCC antibody, GS-X antibody, MRP antibody, MRP1 antibody, Abcc1a antibody, Abcc1b antibody, Mdrap antibody, Mrp1 antibody, Avcc1a antibody, Mrp antibody, ABCC13 antibody, ATP binding cassette subfamily C member 1 antibody, ATP-binding cassette, sub-family C (CFTR/MRP), member 1 antibody, multidrug resistance-associated protein 1 antibody, ABCC1 antibody, Abcc1 antibody, LOC100152428 antibody, LOC100346553 antibody
Background
The two members of the large family of ABC transporters known to confer multidrug resistance in human cancer cells are the MDR1 P-glycoprotein and the multidrug-resistance protein MRP1. MRP1 is an integral membrane protein that contains an MDR-like core, an N-terminal membrane-bound region and a cytoplasmic linker, and it is expressed in various cerebral cells, as well as in lung, testis and peripheral blood.