RSPO2 antibody
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- Target See all RSPO2 Antibodies
- RSPO2 (R-Spondin 2 (RSPO2))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RSPO2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- Immunogen
- R-spondin 2 homolog (Xenopus laevis)
- Isotype
- IgG
- Top Product
- Discover our top product RSPO2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- RSPO2 (R-Spondin 2 (RSPO2))
- Alternative Name
- RSPO2 (RSPO2 Products)
- Synonyms
- RGD1562331 antibody, CRISTIN2 antibody, 2610028F08Rik antibody, AA673245 antibody, D430027K22 antibody, ftls antibody, R-spondin 2 antibody, R-spondin 2 L homeolog antibody, Rspo2 antibody, rspo2.L antibody, rspo2 antibody, RSPO2 antibody
- Background
- Synonyms:CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2 Background:Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6(LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.
- Gene ID
- 340419
- UniProt
- Q6UXX9
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