MLXIP antibody
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- Target See all MLXIP Antibodies
- MLXIP (MLX Interacting Protein (MLXIP))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MLXIP antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Immunogen
- MLX interacting protein
- Isotype
- IgG
- Top Product
- Discover our top product MLXIP Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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K-562 cells were subjected to SDS PAGE followed by western blot with FNab05223(MLXIP antibody) at dilution of 1:500
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- MLXIP (MLX Interacting Protein (MLXIP))
- Alternative Name
- MLXIP (MLXIP Products)
- Synonyms
- MGC83884 antibody, si:ch211-110p13.4 antibody, MIR antibody, MONDOA antibody, bHLHe36 antibody, AW228700 antibody, B930074I24 antibody, Mir antibody, mKIAA0867 antibody, RGD1560774 antibody, MLX interacting protein antibody, MLX interacting protein L homeolog antibody, MLXIP antibody, mlxip.L antibody, mlxip antibody, Mlxip antibody
- Background
- Synonyms:BHLHE36, KIAA0867, MIR, MONDOA Background:Mlx-interacting protein(MLXIP), after forming heterodimers with MLX, can bind to and then activate transcription from CACGTG E boxes. The N terminus of MLXIP acts as a CRM1-dependent nuclear export signal and contribute to the cytoplasmic localization of the complex, and as a binding site for 13 protein. the C terminus contains a cytoplasmic localization signal and mediates protein-protein interaction of MONDOA and MLX. The complex play a role in transcriptional activation of glycolytic target genes and glucose-responsive gene regulation. This antibody could recognize isoform1(~110kd) and isoform3(~69kd) of MLXIP. A specific MLXIP of approximately 130 kDa was detected. It demonstrates that MLXIP associated specifically with Mlx in the cytoplasm (PMID: 11073985).
- Molecular Weight
- 130 kDa
- Gene ID
- 22877
- UniProt
- Q9HAP2
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