ARL4C antibody

Catalog No. ABIN5700277

Product Details anti-ARL4C Antibody

Target: ARL4C (ADP-Ribosylation Factor-Like 4C (ARL4C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARL4C antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Immunogen: ADP-ribosylation factor-like 4C

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for ARL4C

Target: ARL4C (ADP-Ribosylation Factor-Like 4C (ARL4C))

Alternative Name: ARL4C (ARL4C Products)

Background: Synonyms:ARL4C, ARL7, LAK Background:Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP-bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process.

Molecular Weight: 21-25 kDa

Gene ID: 10123

UniProt: P56559