F-Box Protein 3 antibody
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- Target See all F-Box Protein 3 (FBXO3) Antibodies
- F-Box Protein 3 (FBXO3)
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This F-Box Protein 3 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB)
- Immunogen
- F-box protein 3
- Isotype
- IgG
- Top Product
- Discover our top product FBXO3 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- F-Box Protein 3 (FBXO3)
- Alternative Name
- FBXO3 (FBXO3 Products)
- Synonyms
- FBA antibody, FBX3 antibody, 1200002G09Rik antibody, 1700026K02Rik antibody, AI046358 antibody, Fba antibody, zgc:112485 antibody, DKFZp459H187 antibody, F-box protein 3 antibody, F-box protein 3 S homeolog antibody, FBXO3 antibody, Fbxo3 antibody, fbxo3.S antibody, fbxo3 antibody
- Background
- Synonyms:FBX3 Background:Substrate recognition component of the SCF(SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.
- Molecular Weight
- 48-50 kDa
- Gene ID
- 26273
- UniProt
- Q9UK99
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