SMG5 antibody
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- Target See all SMG5 Antibodies
- SMG5 (Smg-5 Homolog, Nonsense Mediated mRNA Decay Factor (SMG5))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SMG5 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Immunogen
- Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)
- Isotype
- IgG
- Top Product
- Discover our top product SMG5 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab08025(SMG5 antibody) at dilution of 1:400
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- SMG5 (Smg-5 Homolog, Nonsense Mediated mRNA Decay Factor (SMG5))
- Alternative Name
- SMG5 (SMG5 Products)
- Synonyms
- BC024683 antibody, mKIAA1089 antibody, EST1B antibody, LPTS-RP1 antibody, LPTSRP1 antibody, SMG-5 antibody, SMG5, nonsense mediated mRNA decay factor antibody, Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) antibody, SMG5 nonsense mediated mRNA decay factor antibody, SMG5 antibody, Smg5 antibody
- Background
- Synonyms:EST1 like protein B, EST1B, hSMG 5, KIAA1089, LPTS interacting protein, LPTS RP1, LPTSRP1, Protein SMG5, RP11 54H19.7, SMG 5, SMG 5 homolog, SMG5 Background:Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A(PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.
- Gene ID
- 23381
- UniProt
- Q9UPR3
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