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SMG5 antibody

SMG5 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5699364
  • Target See all SMG5 Antibodies
    SMG5 (Smg-5 Homolog, Nonsense Mediated mRNA Decay Factor (SMG5))
    Reactivity
    • 19
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 18
    • 1
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    This SMG5 antibody is un-conjugated
    Application
    • 17
    • 14
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Immunogen
    Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)
    Isotype
    IgG
    Top Product
    Discover our top product SMG5 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    HeLa cells were subjected to SDS PAGE followed by western blot with FNab08025(SMG5 antibody) at dilution of 1:400

    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze / thaw cycles.
    Storage
    -20 °C
    Expiry Date
    12 months
  • Target
    SMG5 (Smg-5 Homolog, Nonsense Mediated mRNA Decay Factor (SMG5))
    Alternative Name
    SMG5 (SMG5 Products)
    Synonyms
    BC024683 antibody, mKIAA1089 antibody, EST1B antibody, LPTS-RP1 antibody, LPTSRP1 antibody, SMG-5 antibody, SMG5, nonsense mediated mRNA decay factor antibody, Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) antibody, SMG5 nonsense mediated mRNA decay factor antibody, SMG5 antibody, Smg5 antibody
    Background
    Synonyms:EST1 like protein B, EST1B, hSMG 5, KIAA1089, LPTS interacting protein, LPTS RP1, LPTSRP1, Protein SMG5, RP11 54H19.7, SMG 5, SMG 5 homolog, SMG5 Background:Plays a role in nonsense-mediated mRNA decay. Does not have RNase activity by itself. Promotes dephosphorylation of UPF1. Together with SMG7 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A(PP2A), thereby triggering UPF1 dephosphorylation. Necessary for TERT activity.
    Gene ID
    23381
    UniProt
    Q9UPR3
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