SNX6 antibody
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- Target See all SNX6 Antibodies
- SNX6 (Sorting Nexin 6 (SNX6))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SNX6 antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Immunogen
- sorting nexin 6
- Isotype
- IgG
- Top Product
- Discover our top product SNX6 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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RAW 264.7 cells were subjected to SDS PAGE followed by western blot with FNab08095( SNX6 Antibody) at dilution of 1:600
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze / thaw cycles.
- Storage
- -20 °C
- Expiry Date
- 12 months
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- Target
- SNX6 (Sorting Nexin 6 (SNX6))
- Alternative Name
- SNX6 (SNX6 Products)
- Synonyms
- MGC75952 antibody, MGC80251 antibody, im:7146294 antibody, wu:fa55b10 antibody, zgc:110798 antibody, MSTP010 antibody, TFAF2 antibody, 2010006G21Rik antibody, 2610032J07Rik antibody, 2810425K19Rik antibody, AU018928 antibody, C85963 antibody, sorting nexin 6 antibody, sorting nexin 6 L homeolog antibody, snx6 antibody, snx6.L antibody, SNX6 antibody, Snx6 antibody
- Background
- Synonyms: Background:Involved in several stages of intracellular trafficking. Interacts with membranes phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 4,5-bisphosphate(Probable). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex(PubMed:19935774). The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network(TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier(ETC)(Probable). Does not have in vitro vesicle-to-membrane remodeling activity(PubMed:23085988). Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptor IGF2R(PubMed:17148574). May function as link between transport vesicles and dynactin(Probable). Negatively regulates retrograde transport of BACE1 from the cell surface to the trans-Golgi network(PubMed:20354142). Involved in E-cadherin sorting and degradation, inhibits PIP5K1C isoform 3-mediated E-cadherin degradation(PubMed:24610942). In association with GIT1 involved in EGFR degradation. Promotes lysosomal degradation of CDKN1B(By similarity). May contribute to transcription regulation(Probable).
- Gene ID
- 58533
- UniProt
- Q9UNH7
- Pathways
- EGFR Signaling Pathway
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