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PCSK9 antibody (Internal Region)
PCSK9
Reactivity: Human, Rat, Mouse
WB, EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-PCSK9 Antibody
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Target
See all PCSK9 Antibodies
PCSK9
(Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))
Binding Specificity
All epitopes for PCSK9 antibodies
AA 214-228, Internal Region
Reactivity
Human, Rat, Mouse
Host
All hosts for PCSK9 antibodies
Goat
Clonality
All clonalities for PCSK9 antibodies
Polyclonal
Conjugate
All conjugates for PCSK9 antibodies
This PCSK9 antibody is un-conjugated
Application
All applications for PCSK9 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Sequence
TRFHRQASKC DSHGT
Specificity
Recognizes PCSK9.
Cross-Reactivity (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
Immunogen
Peptide with sequence from the internal region of the protein sequence according to NP_777596.2.
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for PCSK9
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Target
PCSK9
(Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9))
Alternative Name
PCSK9 (PCSK9 Products )
Synonyms
FH3 antibody, HCHOLA3 antibody, LDLCQ1 antibody, NARC-1 antibody, NARC1 antibody, PC9 antibody, AI415265 antibody, AI747682 antibody, Narc1 antibody, proprotein convertase subtilisin/kexin type 9 antibody, proprotein convertase subtilisin/kexin type 9 L homeolog antibody, PCSK9 antibody, pcsk9.L antibody, pcsk9 antibody, Pcsk9 antibody
Background
PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. PCSK9 may function as a proprotein convertase. PCSK9 plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in PCSK9 gene have been associated with a third form of autosomal dominant familial hypercholesterolemia.Synonyms: NARC-1, NARC1, Neural apoptosis-regulated convertase 1, PCSK-9, Proprotein convertase PC9, Proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9
Gene ID
255738
NCBI Accession
NP_777596
UniProt
Q8NBP7
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