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Glutathione Reductase antibody (AA 256-522)

GSR Reactivity: Human, Rat, Mouse WB, IHC, ELISA, ICC, FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5693151
  • Target See all Glutathione Reductase (GSR) Antibodies
    Glutathione Reductase (GSR)
    Binding Specificity
    • 15
    • 15
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 256-522
    Reactivity
    • 53
    • 25
    • 20
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 72
    • 8
    Rabbit
    Clonality
    • 72
    • 8
    Polyclonal
    Conjugate
    • 35
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Glutathione Reductase antibody is un-conjugated
    Application
    • 51
    • 26
    • 26
    • 25
    • 21
    • 17
    • 11
    • 10
    • 10
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Brand
    Picoband™
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Glutathione Reductas detection. Tested with WB, IHC-F, ICC, FCM, Direct ELISA in Human,Mouse,Rat.
    Immunogen
    E. coli-derived human Glutathione Reductase recombinant protein (Position: K256-R522).
    Top Product
    Discover our top product GSR Primary Antibody
  • Application Notes

    Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(F) and ICC.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Target
    Glutathione Reductase (GSR)
    Alternative Name
    GSR (GSR Products)
    Background

    Synonyms: Glutathione reductase, mitochondrial, GR, GRase, GSR, GLUR, GRD1

    Background: Glutathione reductase (GR), also known as glutathione-disulfide reductase (GSR), is an enzyme that in humans is encoded by the GSR gene. This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

    UniProt
    P00390
    Pathways
    Thyroid Hormone Synthesis, Cell RedoxHomeostasis
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