HGD antibody (AA 374-445)

Catalog No. ABIN5693116

Product Details anti-HGD Antibody

Target: HGD (Homogentisate 1,2-Dioxygenase (HGD))

Binding Specificity: AA 374-445

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HGD antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Brand: Picoband™

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for HGD detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human HGD recombinant protein (Position: D374-N445).

Application Details

Application Notes:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Application Details: Western blot,0.1-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section),0.5-1 μg/mL
Direct ELISA,0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Target Details for HGD

Target: HGD (Homogentisate 1,2-Dioxygenase (HGD))

Alternative Name: HGD (HGD Products)

Synonyms: CG4779 antibody, Dmel\\CG4779 antibody, PSPTO3551 antibody, DDBDRAFT_0185702 antibody, DDBDRAFT_0191461 antibody, DDB_0185702 antibody, DDB_0191461 antibody, Hgo antibody, aku antibody, hgo antibody, AKU antibody, HGO antibody, homogentisate 1,2-dioxygenase antibody, Homogentisate 1,2-dioxygenase antibody, homogentisate 1, 2-dioxygenase antibody, homogentisate 1,2-dioxygenase L homeolog antibody, hgo antibody, HGD antibody, hmgA antibody, Shewana3_2481 antibody, hgd antibody, BC1002_0545 antibody, BC1003_0502 antibody, BC1001_0489 antibody, Sinme_2995 antibody, Sphch_0441 antibody, Hgd antibody, hgd.L antibody

Background:

Synonyms: Homogentisate 1,2-dioxygenase, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase, HGD, HGO

Tissue Specificity: Highest expression in the prostate, small intestine, colon, kidney and liver.

Background: The HGD gene encodes homogentisate 1,2-dioxygenase (HGD), an enzyme involved in the catabolism of phenylalanine and tyrosine. This enzyme is involved in the catabolism of the amino acids tyrosine and phenylalanine. Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria. This gene is mapped to chromosome 3q21-q23 by a preliminary PCR screen of hamster/human somatic cell hybrid genomic DNA samples and by fluorescence in situ hybridization.

UniProt: Q93099