PSD antibody (AA 536-803)

Catalog No. ABIN5692916

Product Details anti-PSD Antibody

Target: PSD (Pleckstrin and Sec7 Domain Protein (PSD))

Binding Specificity: AA 536-803

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSD antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Brand: Picoband™

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for PSD detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human PSD recombinant protein (Position: T536-K803).

Application Details

Application Notes:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot,0.1-0.5 μg/mL
Direct ELISA,0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Target Details for PSD

Target: PSD (Pleckstrin and Sec7 Domain Protein (PSD))

Alternative Name: PSD (PSD Products)

Background:

Synonyms: PH and SEC7 domain-containing protein 1, Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6, Exchange factor for ARF6, Exchange factor for ARF6 A, Pleckstrin homology and SEC7 domain-containing protein 1, PSD, EFA6, EFA6A

Tissue Specificity: Isoform 2 is expressed in the brain.

Background: PSD, which called EFA6A, is 63 % identical to EFA6B (PSD4) and contains a Sec7 domain adjacent to a PH domain, followed by a C-terminal coiled-coil motif. This gene is mapped to chromosome 10q24. And it encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants.