Glycerol Kinase antibody (AA 1-180)

Catalog No. ABIN5692865

Product Details anti-Glycerol Kinase Antibody

Target: Glycerol Kinase (GK)

Binding Specificity: AA 1-180

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glycerol Kinase antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Brand: Picoband™

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Glycerol kinase detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human Glycerol kinase recombinant protein (Position: M1-S180).

Application Details

Application Notes:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Target Details for Glycerol Kinase

Target: Glycerol Kinase (GK)

Alternative Name: GK (GK Products)

Synonyms: GK1 antibody, GKD antibody, D930012N15Rik antibody, GK antibody, CG18374 antibody, Dmel\\CG18374 antibody, dGyk antibody, ASTP antibody, Gyk antibody, gk1 antibody, gk2 antibody, gkd antibody, gyk antibody, Gk antibody, BmGK antibody, DKFZp469P1225 antibody, glycerol kinase antibody, Glycerol kinase 1 antibody, glycerol kinase S homeolog antibody, putative glycerol kinase 3 antibody, ATP:glycerol 3-phosphotransferase; glycerokinase; GK antibody, Glycerol kinase antibody, Fanconi anemia core complex associated protein 100 antibody, GK antibody, Gk antibody, Gk1 antibody, gk.S antibody, LOC705001 antibody, glpK antibody, Spico_1557 antibody, Trebr_0397 antibody, Halhy_5315 antibody, gk antibody, FAAP100 antibody

Background:

Synonyms: Glycerol kinase, GK, Glycerokinase, ATP:glycerol 3-phosphotransferase, GK

Tissue Specificity: Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver.

Background: Glycerol kinase is a phosphotransferase enzyme involved in triglycerides and glycerophospholipids synthesis. The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: P32189