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TMEM107 antibody (AA 20-70)

TMEM107 Reactivity: Human WB, IHC (p), ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5690294
  • Target See all TMEM107 products
    TMEM107 (Transmembrane Protein 107 (TMEM107))
    Binding Specificity
    • 2
    • 1
    • 1
    • 1
    AA 20-70
    Reactivity
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 12
    Rabbit
    Clonality
    • 12
    Polyclonal
    Conjugate
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TMEM107 antibody is un-conjugated
    Application
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunofluorescence (IF)
    Specificity
    TMEM107 antibody is human specific. At least two isoforms of TMEM107 are known to exist.
    Purification
    TMEM107 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    TMEM107 antibody was raised against a 19 amino acid peptide near the amino terminus of human TMEM107.

    The immunogen is located within amino acids 20 - 70 of TMEM107 .
    Isotype
    IgG
  • Application Notes
    TMEM107 antibody can be used for detection of TMEM107 by Western blot at 1 - 2 μ,g/mL.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    TMEM107 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    TMEM107antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    TMEM107 (Transmembrane Protein 107 (TMEM107))
    Alternative Name
    TMEM107 (TMEM107 Products)
    Synonyms
    zgc:77926 antibody, MGC157051 antibody, GRVS638 antibody, PRO1268 antibody, 1110004B13Rik antibody, 2810049P21Rik antibody, transmembrane protein 107 antibody, Transmembrane protein 107 antibody, transmembrane protein 107 L homeolog antibody, tmem107 antibody, TMEM107 antibody, Tmem107 antibody, Tsp_08866 antibody, tm107 antibody, tmem107.L antibody
    Background
    Transmembrane protein 107 (TMEM 107) is critical for cilia formation and embryonic patterning (1). It is a 139 amino acid transmembrane protein encoded by a gene that maps to human chromosome 17 which is associated with two key tumor suppressor genes p53 and BRCA1 (1,2). TMEM107 is required for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with Gli2 and Gli3 to pattern ventral and intermediate neuronal cell types (1,3). TMEM107 is also a strong candidate gene for central areolar choroidal dystrophy (CACD) (1-3).
    Molecular Weight
    Predicted: 16 kDa

    Observed: 19kDa
    Gene ID
    84314
    NCBI Accession
    NP_115730
    UniProt
    Q6UX40
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