SLC1A7
Reactivity: Human
Host: Rabbit
Polyclonal
FITC
Application Notes
SLC1A7 antibody can be used for detection of SLC1A7 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
SLC1A7 antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
SLC1A7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target
SLC1A7
(Solute Carrier Family 1 (Glutamate Transporter), Member 7 (SLC1A7))
SLC1A7 antibody, si:ch211-284b7.1 antibody, slc1a7 antibody, A930031E15Rik antibody, Eaat5 antibody, AAAT antibody, EAAT5 antibody, solute carrier family 1 member 7 antibody, solute carrier family 1 (glutamate transporter), member 7a antibody, solute carrier family 1 (glutamate transporter), member 7 antibody, SLC1A7 antibody, slc1a7a antibody, Slc1a7 antibody
Background
The solute carrier family 1 member 7 (SLC1A7) protein was initially identified as a glutamate transporter coupled to a chloride conductance that is expressed primarily in the retina (1). More recent evidence indicates that is it widely expressed in peripheral tissues, also (2). Experiments have shown that SLC1A7 functions as a low-affinity/low-capacity glutamate transport, with an anion channel optimized for anion conductance in the negative voltage range (3). In the retina, SLC1A7 co-localizes with the serum and glucocorticoid dependent kinase SGK1, and its cell surface expression and activity is regulated SGK1 and its isoform SGK3 (4).