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ERAP2 antibody (AA 110-160)
ERAP2
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ERAP2 Antibody
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Target
See all ERAP2 Antibodies
ERAP2
(Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))
Binding Specificity
All epitopes for ERAP2 antibodies
AA 110-160
Reactivity
All reactivities for ERAP2 antibodies
Human
Host
All hosts for ERAP2 antibodies
Rabbit
Clonality
All clonalities for ERAP2 antibodies
Polyclonal
Conjugate
All conjugates for ERAP2 antibodies
This ERAP2 antibody is un-conjugated
Application
All applications for ERAP2 antibodies
Western Blotting (WB), ELISA
Specificity
ERAP2 antibody is human reactive. Multiple isoforms of ERAP2 are known to exist. ERAP2 antibody is predicted to not cross-react with ERAP1.
Purification
ERAP2 Antibody is affinity chromatography purified via peptide column.
Immunogen
ERAP2 antibody was raised against a 17 amino acid peptide near the amino terminus of human ERAP2. The immunogen is located within amino acids 110 - 160 of ERAP2 .
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
ERAP2 antibody can be used for detection of ERAP2 by Western blot at 1 - 2 μ,g/mL.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
ERAP2 Antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
ERAP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target Details for ERAP2
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Target
ERAP2
(Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))
Alternative Name
ERAP2 (ERAP2 Products )
Background
The endoplasmic reticulum (ER) aminopeptidase 2 (ERAP2), a member of the peptidase M1 family, like the related protein ERAP1, plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides (1,2). Like ERAP1, ERAP2 is localized to the lumen of the ER and is thought to associate with ERAP1 as a heterodimer (1). Both ERAP1 and ERAP2 have been linked to several human diseases ranging from infections to autoimmunity and cancer, and may play a role in the innate immune response (reviewed in 3).
Molecular Weight
Predicted: 106 kDa Observed: 120kDa
Gene ID
64167
NCBI Accession
NP_071745
UniProt
Q6P179
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