1300002L19Rik antibody, Cdo antibody, D18Ucla3 antibody, cysteine dioxygenase, type I antibody, cysteine dioxygenase 1, cytosolic antibody, cysteine dioxygenase type 1 antibody, NAEGRDRAFT_80458 antibody, Cdo1 antibody, CDO1 antibody
Background
CDO1 (cysteine dioxygenase, type I) belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis (1). CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine (1,2). CDO1 exists as a monomer and is expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart (1). CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell (3,4).