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ATM Interactor antibody (AA 200-250)

ATMIN Reactivity: Human, Mouse, Rat WB, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5689887
  • Target See all ATM Interactor (ATMIN) Antibodies
    ATM Interactor (ATMIN)
    Binding Specificity
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 200-250
    Reactivity
    • 21
    • 13
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 19
    • 2
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATM Interactor antibody is un-conjugated
    Application
    • 11
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    ATMIN antibody is human, mouse and rat reactive. At least three isoforms of ATMIN are known to exist.
    Purification
    ATMIN antibody is affinity chromatography purified via peptide column.
    Immunogen
    ATMIN antibody was raised against a 19 amino acid peptide near the amino terminus of human ATMIN.

    The immunogen is located within amino acids 200 - 250 of ATMIN.
    Isotype
    IgG
    Top Product
    Discover our top product ATMIN Primary Antibody
  • Application Notes
    ATMIN antibody can be used for detection of ATMIN by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry at 5 μ,g/mL. For Immunoflorescence start at 2.5 μ,g/mL.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    ATMIN Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    ATMIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    ATM Interactor (ATMIN)
    Alternative Name
    ATMIN (ATMIN Products)
    Synonyms
    Asciz antibody, mKIAA0431 antibody, RGD1305781 antibody, ASCIZ antibody, ZNF822 antibody, ATM interactor antibody, ATM interactor L homeolog antibody, Atmin antibody, ATMIN antibody, atmin.L antibody, atmin antibody
    Background
    The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51 (1). ATMIN is also thought to be involved in embryonic development, as an absence of ATMIN causes late-embryonic lethality in mice with a range of organ development defects (2). It also activates the transcription DYNLL1, a light chain of the dynein motor complex and sequence-specific regulator of protein dimerization of numerous targets. DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a simple dynamic feedback loop for DYNLL1 expression (3).
    Molecular Weight
    Predicted: 73, 79, 91 kDa

    Observed: 72 kDa
    Gene ID
    23300
    NCBI Accession
    NP_056066
    UniProt
    O43313
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