AKAP4
Reactivity: Human
WB, ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
AKAP4 antibody can be used for detection of AKAP4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
AKAP4 antibody is supplied in PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
AKAP4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
AKAP4 antibody, AKAP 82 antibody, AKAP-4 antibody, AKAP82 antibody, CT99 antibody, FSC1 antibody, HI antibody, PRKA4 antibody, hAKAP82 antibody, p82 antibody, Fsc1 antibody, A-kinase anchoring protein 4 antibody, A kinase (PRKA) anchor protein 4 antibody, AKAP4 antibody, Akap4 antibody
Background
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell (1). AKAP4, also known as hAKAP82, is a major sperm fibrous sheath protein that localizes to the entire length of the flagellum of human sperm (2). It has been suggested that AKAP4 plays multiple roles in sperm motility and regulation of signal transduction pathways (2). AKAP4 has also been postulated to be a potential biomarker for breast cancer (3).