CHRNE antibody (AA 28-163)

Catalog No. ABIN5684150

Product Details anti-CHRNE Antibody

Target: CHRNE (Cholinergic Receptor, Nicotinic, epsilon (Muscle) (CHRNE))

Binding Specificity: AA 28-163

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CHRNE antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human CHRNE (AA: extra 21-239) expressed in E. coli.

Clone: 3A5G12

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for CHRNE

Target: CHRNE (Cholinergic Receptor, Nicotinic, epsilon (Muscle) (CHRNE))

Alternative Name: CHRNE (CHRNE Products)

Synonyms: ACHRE antibody, CMS1D antibody, CMS1E antibody, CMS2A antibody, FCCMS antibody, SCCMS antibody, AChrepsilon antibody, Acre antibody, nAChRE antibody, im:7154697 antibody, zgc:101010 antibody, CHRNE antibody, cholinergic receptor nicotinic epsilon subunit antibody, cholinergic receptor, nicotinic, epsilon polypeptide antibody, cholinergic receptor, nicotinic epsilon L homeolog antibody, cholinergic receptor, nicotinic, epsilon antibody, CHRNE antibody, Chrne antibody, chrne.L antibody, chrne antibody

Background:

Description: Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.

Aliases: ACHRE, CMS1D, CMS1E, CMS2A, CMS4A, CMS4B, CMS4C, FCCMS, SCCMS

Molecular Weight: 54.7 kDa

Gene ID: 1145

HGNC: 3383