LAIR1 antibody (AA 22-165)
-
- Target See all LAIR1 Antibodies
- LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
-
Binding Specificity
- AA 22-165
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This LAIR1 antibody is un-conjugated
-
Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- CD305 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CD305 (AA: 22-165) expressed in E. Coli.
- Clone
- 1G8B6
- Isotype
- IgG1
- Top Product
- Discover our top product LAIR1 Primary Antibody
-
-
- Application Notes
-
ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
- Target
- LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
- Alternative Name
- CD305 (LAIR1 Products)
- Synonyms
- 5133400O11Rik antibody, BB115266 antibody, D7Bwg0421e antibody, Lair-1 antibody, mLair-1 antibody, CD305 antibody, LAIR-1 antibody, leukocyte-associated Ig-like receptor 1 antibody, leukocyte associated immunoglobulin like receptor 1 antibody, leukocyte-associated immunoglobulin-like receptor 1 antibody, Lair1 antibody, LAIR1 antibody
- Background
-
Description: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.
Aliases: LAIR1, LAIR-1
- Molecular Weight
- 31.4kDa
- Gene ID
- 3903
- HGNC
- 967
- UniProt
- Q6GTX8
-