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LAIR1 antibody (AA 22-165)

LAIR1 Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 1G8B6 unconjugated
Catalog No. ABIN5684133
  • Target See all LAIR1 Antibodies
    LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
    Binding Specificity
    • 9
    • 7
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-165
    Reactivity
    • 51
    • 12
    • 1
    Human
    Host
    • 37
    • 13
    • 2
    • 1
    Mouse
    Clonality
    • 40
    • 13
    Monoclonal
    Conjugate
    • 24
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LAIR1 antibody is un-conjugated
    Application
    • 34
    • 24
    • 10
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Purpose
    CD305 Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CD305 (AA: 22-165) expressed in E. Coli.
    Clone
    1G8B6
    Isotype
    IgG1
    Top Product
    Discover our top product LAIR1 Primary Antibody
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
    Alternative Name
    CD305 (LAIR1 Products)
    Synonyms
    5133400O11Rik antibody, BB115266 antibody, D7Bwg0421e antibody, Lair-1 antibody, mLair-1 antibody, CD305 antibody, LAIR-1 antibody, leukocyte-associated Ig-like receptor 1 antibody, leukocyte associated immunoglobulin like receptor 1 antibody, leukocyte-associated immunoglobulin-like receptor 1 antibody, Lair1 antibody, LAIR1 antibody
    Background

    Description: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.

    Aliases: LAIR1, LAIR-1

    Molecular Weight
    31.4kDa
    Gene ID
    3903
    HGNC
    967
    UniProt
    Q6GTX8
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