CD3D antibody (AA 22-105)

Catalog No. ABIN5684129

Product Details anti-CD3D Antibody

Target: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Binding Specificity: AA 22-105

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD3D antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: CD3D Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD3D (AA: 22-105) expressed in E. Coli.

Clone: 1F6A8

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CD3D

Target: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Alternative Name: CD3D (CD3D Products)

Synonyms: CD3-DELTA antibody, T3D antibody, CD3 antibody, T3d antibody, CD3d molecule antibody, CD3 antigen, delta polypeptide antibody, CD3D antibody, Cd3d antibody

Background:

Description: The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

Aliases: T3D, IMD19, CD3-DELTA

Molecular Weight: 18.9kDa

Gene ID: 915

HGNC: 10666

UniProt: P04234

Pathways: TCR Signaling, CXCR4-mediated Signaling Events