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CD8 alpha antibody (AA 22-182)

CD8A Reactivity: Human FACS, IHC, WB, ELISA, ICC, Neut Host: Mouse Monoclonal 5H5D7 unconjugated
Catalog No. ABIN5684128
  • Target See all CD8 alpha (CD8A) Antibodies
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Binding Specificity
    • 16
    • 15
    • 10
    • 9
    • 9
    • 9
    • 8
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-182
    Reactivity
    • 184
    • 105
    • 47
    • 39
    • 15
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 146
    • 127
    • 92
    Mouse
    Clonality
    • 258
    • 103
    • 1
    Monoclonal
    Conjugate
    • 115
    • 43
    • 35
    • 27
    • 26
    • 10
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD8 alpha antibody is un-conjugated
    Application
    • 287
    • 124
    • 86
    • 64
    • 58
    • 42
    • 20
    • 18
    • 15
    • 14
    • 13
    • 9
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Neutralization (Neut)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human CD8A (AA: extra 22-182) expressed in E. coli.
    Clone
    5H5D7
    Isotype
    IgG1
    Top Product
    Discover our top product CD8A Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Alternative Name
    CD8A (CD8A Products)
    Synonyms
    cd8 antibody, LOC100136450 antibody, BB154331 antibody, Ly-2 antibody, Ly-35 antibody, Ly-B antibody, Lyt-2 antibody, zgc:136643 antibody, CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody, RHACD8-4 antibody, CD8a molecule antibody, uncharacterized LOC100125537 antibody, CD8 alpha antibody, CD8 antigen, alpha chain antibody, T-cell surface glycoprotein CD8 alpha chain antibody, Cd8a antibody, LOC100125537 antibody, LOC100136450 antibody, CD8A antibody, cd8a antibody, LOC100126556 antibody
    Background

    Description: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

    Aliases: CD8, MAL, p32, Leu2

    Molecular Weight
    25.7 kDa
    Gene ID
    925
    HGNC
    5789
    Pathways
    TCR Signaling
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