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Ancient Ubiquitous Protein 1 antibody (AA 229-410)

Aup1 Reactivity: Human, Mouse WB, ELISA, IHC, ICC, FACS, Neut Host: Mouse Monoclonal 7G4A6 unconjugated
Catalog No. ABIN5684097
  • Target See all Ancient Ubiquitous Protein 1 (Aup1) Antibodies
    Ancient Ubiquitous Protein 1 (Aup1)
    Binding Specificity
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    AA 229-410
    Reactivity
    • 29
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 31
    • 1
    Mouse
    Clonality
    • 32
    Monoclonal
    Conjugate
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Ancient Ubiquitous Protein 1 antibody is un-conjugated
    Application
    • 25
    • 15
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human AUP1 (AA: 229-410) expressed in E. coli.
    Clone
    7G4A6
    Isotype
    IgG2b
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: N/A
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    Ancient Ubiquitous Protein 1 (Aup1)
    Alternative Name
    AUP1 (Aup1 Products)
    Synonyms
    AA589454 antibody, wu:fc37d06 antibody, zgc:73323 antibody, zgc:77755 antibody, AUP1, lipid droplet regulating VLDL assembly factor antibody, ancient ubiquitous protein 1 antibody, ancient ubiquitous protein 1 S homeolog antibody, AUP1 antibody, aup1 antibody, Aup1 antibody, aup1.S antibody
    Background
    The protein encoded this gene is involved in several pathways including quality control of misfolded proteins in the endoplasmic reticulum and lipid droplet accumulation. Lipid droplets are organelles in the cytoplasm that store neutral lipids such as cholesterol esters and trigylycerides to prevent the overabundance of free cholesterol and fatty acids in cells, but also to act as storage for other metabolic processes, such as membrane biogenesis. Reduced expression of this gene results in reduced lipid droplet clustering, a function that is dependent on ubiquitination of the protein. This protein contains multiple domains including a hydrophobic N-terminal domain, an acetyltranferase domain, a ubiquitin-binding CUE domain, and a UBE2B2-binding domain (G2BR). Alternative splicing results in multiple transcript variants.
    Molecular Weight
    53 kDa
    Gene ID
    550
    HGNC
    27180
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