Histone Cluster 2, H4a (HIST2H4A) (meLys20) antibody

Catalog No. ABIN5684092

Product Details

Target: Histone Cluster 2, H4a (HIST2H4A)

Binding Specificity: meLys20

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Purpose: HIST2H4A (20Me) Antibody

Purification: Purified antibody

Immunogen: Synthesized peptide of human HIST2H4A ( AA: GGAKRHRK(Me)VLRDNIQ ).

Clone: 3E7H2

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details

Target: Histone Cluster 2, H4a (HIST2H4A)

Alternative Name: HIST2H4A (HIST2H4A Products)

Synonyms: FO108 antibody, H4 antibody, H4/n antibody, H4F2 antibody, H4FN antibody, HIST2H4 antibody, X04652 antibody, Hist4h4 antibody, histone cluster 2 H4 family member a antibody, histone cluster 2, H4 antibody, histone H4 antibody, HIST2H4A antibody, Hist2h4 antibody, HIST2H4 antibody

Background:

Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the centromeric copy.

Aliases: H4, H4/n, H4F2, H4FN, FO108, HIST2H4

Molecular Weight: 11.4kDa

Gene ID: 8370

HGNC: 8370

UniProt: P62805

Pathways: Telomere Maintenance