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ITGA2 antibody (AA 994-1132)

ITGA2 Reactivity: Human FACS, WB, IHC, ELISA, ICC, Neut Host: Mouse Monoclonal 8A11A2 unconjugated
Catalog No. ABIN5684082
  • Target See all ITGA2 Antibodies
    ITGA2 (Integrin alpha 2 (ITGA2))
    Binding Specificity
    • 14
    • 8
    • 8
    • 6
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 994-1132
    Reactivity
    • 123
    • 60
    • 22
    • 11
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 79
    • 43
    • 19
    • 5
    • 5
    Mouse
    Clonality
    • 81
    • 73
    Monoclonal
    Conjugate
    • 62
    • 24
    • 17
    • 14
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ITGA2 antibody is un-conjugated
    Application
    • 66
    • 63
    • 41
    • 37
    • 14
    • 12
    • 11
    • 10
    • 10
    • 6
    • 5
    • 3
    • 2
    • 2
    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Neutralization (Neut)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human CD49B (AA: extra 994-1132) expressed in E. coli.
    Clone
    8A11A2
    Isotype
    IgG1
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:100 - 1:500, FCM: 1:200 - 1:400, IHC: N/A
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Target
    ITGA2 (Integrin alpha 2 (ITGA2))
    Alternative Name
    CD49B (ITGA2 Products)
    Synonyms
    BR antibody, CD49B antibody, GPIa antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody, DX5 antibody, integrin subunit alpha 2 antibody, integrin alpha 2 antibody, ITGA2 antibody, Itga2 antibody
    Background

    Description: This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

    Aliases: ITGA2, BR, GPIa, HPA-5, VLA-2, VLAA2

    Molecular Weight
    129.3 kDa
    Gene ID
    3673
    HGNC
    9882
    Pathways
    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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