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TXNIP antibody

TXNIP Reactivity: Human, Mouse WB, IP Host: Mouse Monoclonal JY1 unconjugated
Catalog No. ABIN567793
  • Target See all TXNIP Antibodies
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    Reactivity
    • 67
    • 47
    • 33
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 77
    • 4
    Mouse
    Clonality
    • 69
    • 12
    Monoclonal
    Conjugate
    • 30
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TXNIP antibody is un-conjugated
    Application
    • 57
    • 32
    • 15
    • 14
    • 14
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Specificity
    This antibody reacts with VDUP-1 (50 kDa) by Western blotting.
    Purification
    Protein-A Agarose Chromatography of hybridoma supernatant.
    Immunogen
    Human recombinant VDUP-1/Txnip.
    Clone
    JY1
    Isotype
    IgG2b
    Top Product
    Discover our top product TXNIP Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.2 containing 50 % Glycerol without preservatives.
    Preservative
    Without preservative
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at -20 °C.
  • Target
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    Alternative Name
    TXNIP / VDUP1 (TXNIP Products)
    Synonyms
    EST01027 antibody, HHCPA78 antibody, THIF antibody, VDUP1 antibody, Gm348 antibody, Trf3 antibody, TBP2 antibody, TRF3 antibody, 1200008J08Rik antibody, AA682105 antibody, Hyplip1 antibody, Tbp-2 antibody, Vdup1 antibody, sb:cb368 antibody, txnip antibody, thioredoxin interacting protein antibody, TATA box binding protein like 2 antibody, TATA-box binding protein like 2 antibody, thioredoxin interacting protein L homeolog antibody, thioredoxin interacting protein a antibody, TXNIP antibody, Tbpl2 antibody, TBPL2 antibody, Txnip antibody, txnip.L antibody, txnip antibody, txnipa antibody
    Background
    Vitamin D3 up-regulated protein 1 (VDUP-1), also called Thioredoxin (TRX)-interacting protein, is an endogenous inhibitor of TRX. Redox-dependent regulation of VDUP-1 by mitogenic factors through Reactive oxygen species (ROS) and the specific binding of VDUP-1 to the redox-sensitive cysteine-sulfide center of TRX modulate intracellular levels of ROS and the mitogenic activity of TRX.Synonyms: Thioredoxin-binding protein 2, Thioredoxin-interacting protein, Vitamin D3 up-regulated protein 1
    Gene ID
    10628
    NCBI Accession
    NP_006463
    UniProt
    Q9H3M7
    Pathways
    Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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