EXD2 antibody (AA 351-621) (Biotin)

Catalog No. ABIN5675763

Product Details anti-EXD2 Antibody (Biotin)

Target: EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))

Binding Specificity: AA 351-621

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXD2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: WB shows isoform 2

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EXD2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for EXD2

Target: EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))

Alternative Name: EXD2 (EXD2 Products)

Synonyms: C14orf114 antibody, EXDL2 antibody, 4930539P14Rik antibody, C85658 antibody, Exdl2 antibody, RGD1311087 antibody, exd2-b antibody, exdl2 antibody, fi72h12 antibody, wu:fi72h12 antibody, zgc:175195 antibody, exd2 antibody, exd2-a antibody, exonuclease 3'-5' domain containing 2 antibody, exonuclease 3'-5' domain containing 2 b antibody, EXD2 antibody, Exd2 antibody, exd2.S antibody, exd2 antibody, exd2.L antibody

Background:

Synonyms: Exonuclease 3'-5' domain-containing protein 2, EXD2, C14orf114, EXDL2

Background: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

Gene ID: 55218

UniProt: Q9NVH0