EXD2 antibody (AA 351-621) (AbBy Fluor® 647)
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- Target See all EXD2 products
- EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))
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Binding Specificity
- AA 351-621
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This EXD2 antibody is conjugated to AbBy Fluor® 647
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Specificity
- WB shows isoform 2
- Cross-Reactivity
- Human, Mouse, Rat
- Predicted Reactivity
- Dog,Cow,Sheep,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human EXD2
- Isotype
- IgG
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))
- Alternative Name
- EXD2 (EXD2 Products)
- Synonyms
- C14orf114 antibody, EXDL2 antibody, 4930539P14Rik antibody, C85658 antibody, Exdl2 antibody, RGD1311087 antibody, exd2-b antibody, exdl2 antibody, fi72h12 antibody, wu:fi72h12 antibody, zgc:175195 antibody, exd2 antibody, exd2-a antibody, exonuclease 3'-5' domain containing 2 antibody, exonuclease 3'-5' domain containing 2 b antibody, EXD2 antibody, Exd2 antibody, exd2.S antibody, exd2 antibody, exd2.L antibody
- Background
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Synonyms: Exonuclease 3'-5' domain-containing protein 2, EXD2, C14orf114, EXDL2
Background: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.
- Gene ID
- 55218
- UniProt
- Q9NVH0
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